Demystify Meds for Moderate to Severe Crohn’s Disease

We’re getting questions about how to manage moderate to severe Crohn’s disease...due to a new indication for upadacitinib (Rinvoq).

Continue to use shared-decision making and lean toward a “top-down” approach...with earlier use of biologics before steroid dependence or disease progression. And work closely with GI colleagues.

Biologics include TNF-alpha blockers (adalimumab, etc)...anti-interleukin meds (ustekinumab, etc)...and selective adhesion blockers (vedolizumab, etc).

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