Be Ready to Monitor Vancomycin With AUC/MIC Goals

May 2020

You’ll see a shift toward monitoring vancomycin using AUC/MIC calculations instead of trough levels.

We normally aim for troughs of 15 to 20 mg/L for serious MRSA infections...to increase the likelihood of AUC/MIC over 400 mg*hr/L.

But it turns out these troughs can overshoot AUC/MIC goals...and are linked to more nephrotoxicity.

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