Weigh Pros and Cons of First-Line Meds for C. diff

August 2021

Debate will brew about first-line meds for C. difficile...based on differing recommendations in new guidelines.

We know that oral metronidazole has fallen out of favor...because it’s less effective than vancomycin.

The American College of Gastroenterology now recommends either oral vancomycin or Dificid (fidaxomicin) for a first C. diff episode.

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