add carbamazepine (Tegretol) to the list of drugs that can interact with grapefruit juice

December 1998

You can now add carbamazepine (Tegretol) to the list of drugs that can interact with grapefruit juice.

Grapefruit juice interacts with many drugs...lovastatin...most calcium channel blockers...oral midazolam...triazolam...and cyclosporine.

Grapefruit increases the absorption of these drugs by inhibiting cytochrome 3A4 enzymes in the GI tract.

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Table of Contents

a backlash from managed care against all the drug ads on TV, radio, magazines, etc
Infectious Diseases higher doses of amoxicillin for acute otitis media in children
Infectious Diseases new precautions about liver toxicity with the new quinolone, Trovan (trovafloxacin)
Interactions add carbamazepine (Tegretol) to the list of drugs that can interact with grapefruit juice
new drugs coming out for rheumatoid arthritis
Neurology & Pain new boxed warning about serious liver toxicity in patients taking Tasmar (tolcapone)
Women's Health which antiepileptic drugs interact with oral contraceptives (OCs)
Women's Health The National Cancer Institute is now offering a "Risk Disk"
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Pediatrics Versed (midazolam) now comes as an ORAL syrup
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the first generic cyclosporine, SangCya (sang-see-ah)
Substance Use Disorder reclassify Marinol (dronabinol) from Schedule II to Schedule III
Substance Use Disorder people getting addicted to OTC stimulants
Substance Use Disorder first OTC drug abuse test that can be performed AT HOME
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