possible increased risk of cleft lip and palate in babies exposed to Lamictal during pregnancy

November 2006

The FDA is warning about a possible increased risk of cleft lip and palate in babies exposed to Lamictal during pregnancy.

This is due to a recent report from the North American Antiepileptic Drug (NAAED) Pregnancy Registry.

But the risk seems low...an increase from 0.05% to 0.3% in general to 0.9% in babies exposed to Lamictal (lamotrigine).

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