what to do when an antimicrobial is prescribed with warfarin

February 2009

Winter infections will bring up questions about what to do when an antimicrobial is prescribed with warfarin.

Some antibiotics are more likely than others to affect INR... due to a direct effect on warfarin metabolism.

Warfarin's effect can be INCREASED with metronidazole... macrolides... quinolones... sulfonamides... and azoles.

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