Help Put the Risk of Dementia with PPIs in Perspective

April 2016

Bad press about dementia and other side effects will raise more questions about appropriate use of PPIs (omeprazole, etc).

PPIs are popular because they're so effective and heartburn is common. But up to 70% of PPI use is probably unnecessary.

And PPIs have potential harms. Long-term use is associated with fractures, C. diff diarrhea, pneumonia, hypomagnesemia, and other risks.

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